A healthy 34-year-old woman, 14 weeks pregnant, attends a travel clinic 4 weeks before a 3-week trip to rural sub-Saharan Africa, a region with chloroquine-resistant Plasmodium falciparum. She will stay in non-air-conditioned lodging without window screens. She takes prenatal vitamins only, has no known drug allergies, and has no history of psychiatric illness or seizures. She is anxious about contracting malaria while pregnant. On examination she is well, and the pregnancy is progressing normally.
| Heart rate | 78/min |
| Respiratory rate | 14/min |
| Temperature | 36.8 °C |
| O2 saturation | 99%, room air |
| Blood pressure | 112/68 mm Hg |
Question 1 of 6
Which one of the following is the most appropriate malaria chemoprophylaxis for this patient?
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