A 42-year-old woman comes to your office for pre-travel advice. She leaves in 2 days for a 3-week trip to a rural area of sub-Saharan Africa where chloroquine-resistant Plasmodium falciparum is endemic. She has a history of a seizure disorder, which has been controlled with lamotrigine, and has been seizure-free for 3 years. She has no psychiatric history and no known drug allergies. A urine pregnancy test is negative, her renal function is normal (eGFR 98 mL/min/1.73 m2), and G6PD status has never been tested.
| Heart rate | 72/min |
| Respiratory rate | 14/min |
| Temperature | 36.8 °C |
| O2 saturation | 99%, room air |
| Blood pressure | 118/72 mm Hg |
Question 1 of 6
Which of the following are the most appropriate chemoprophylaxis options for this patient?
Select 2. (0 / 2 selected)
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