A 32-year-old woman, gravida 2 para 1, at 24 weeks' gestation presents with 3 days of progressive left leg swelling and pain. She has no chest pain, dyspnea, or hemoptysis. She has no personal or family history of venous thromboembolism, takes only prenatal vitamins, and has no known drug allergies. Her weight is 78 kg. On examination, the left calf is 3 cm larger in circumference than the right, with tenderness along the thigh. Compression ultrasound shows a non-compressible left common femoral vein with echogenic thrombus. Hemoglobin is 118 g/L (115-155), platelets 245 x 10^9/L (150-400), and creatinine 58 umol/L (45-90).
| Heart rate | 88/min |
| Respiratory rate | 16/min |
| Temperature | 37.1 °C |
| O2 saturation | 98%, room air |
| Blood pressure | 118/72 mm Hg |
Question 1 of 45
Which one of the following is the most appropriate anticoagulant therapy for this patient?
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