Case 1 of 8Multisystem (e.g., Lyme disease, HIV)
A 41-year-old man with newly diagnosed HIV infection is being counselled about opportunistic infection (OI) risk and prophylaxis at different stages of immunosuppression. For each CD4 count threshold below, select the statement that correctly identifies the associated opportunistic infection risk and the appropriate (Canadian-guideline-concordant) prophylactic strategy.
Question 1 of 30
All CD4 counts?
Select 1. (0 / 1 selected)
A. No preventive measures are indicated until the CD4 count falls below 500 cells/µL
B. Start weekly azithromycin in every newly diagnosed HIV patient irrespective of CD4 count
C. Regardless of CD4 count, ensure age/immunosuppression-appropriate vaccination (influenza, pneumococcal, hepatitis A/B, HPV, meningococcal, Tdap) and screen for latent TB (TST or IGRA); treat a positive latent TB screen with isoniazid + pyridoxine for 9 months (rifampin 4 months as an alternative)
D. Start TMP-SMX prophylaxis in every newly diagnosed HIV patient irrespective of CD4 count
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