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Mixed Practice 10

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Case 1 of 10Pregnancy and Reproductive HealthInfertility (e.g., polycystic ovarian syndrome)

A 29-year-old nulligravid woman presents with 14 months of unprotected intercourse without conception. Her menses have occurred every 2 to 4 months since adolescence. She takes no medications and has no known allergies. On examination, BMI is 32 kg/m2, with facial acne and coarse hair on the chin and lower abdomen. Investigations show a normal TSH and prolactin, an elevated total testosterone, and a progesterone level on day 21 of her cycle of 3 nmol/L (luteal phase above 30). Her 31-year-old partner has a normal semen analysis, and hysterosalpingography shows normal uterine cavity and bilateral tubal patency.

Heart rate76/min
Temperature36.8 °C
Blood pressure122/78 mm Hg

Question 1 of 30

Which of the following are the most appropriate first-line medications to induce ovulation?

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