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Mental Health — Trauma- and stressor-related disorders

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Case 1 of 2Mental HealthTrauma- and stressor-related disorders (e.g., adjustment disorder, prolonged grief disorder, posttraumatic stress disorder)

A 32-year-old veteran presents to your clinic with a 4-month history of agitation, insomnia, and recurrent flashbacks of combat events. He avoids news coverage and conversations about the war, feels emotionally numb and detached from his family, and reports persistent guilt about his unit's losses. On examination, he is easily startled, hypervigilant, and anxious. The rest of the physical examination is normal.

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This presentation meets criteria for post-traumatic stress disorder (PTSD). What is the most appropriate first pharmacological treatment option?

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