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Hematologic — Hematologic emergencies

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Case 1 of 3HematologicHematologic emergencies (e.g., febrile neutropenia, sickle cell crisis)

A 60-year-old man presents to the emergency department with fever and pain around the anus that began 12 hours ago. He had a right hemicolectomy for colon cancer 4 months ago and received his latest cycle of adjuvant chemotherapy 8 days ago through an implanted venous port. He has no known drug allergies. On examination he appears unwell, the port site is clean, and there is perianal tenderness without visible swelling, fluctuance or drainage. Laboratory results: WBC 0.4 x10^9/L (4.0-11.0), neutrophils 0.1 x10^9/L (1.8-7.5), hemoglobin 98 g/L (130-170), platelets 88 x10^9/L (150-400), creatinine 88 umol/L (60-110).

Heart rate112/min
Respiratory rate20/min
Temperature38.6 °C
O2 saturation97%, room air
Blood pressure112/68 mm Hg

Question 1 of 9

Which of the following are the most appropriate initial management steps?

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