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Hematologic — Anemia

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Case 1 of 4HematologicAnemia (e.g., iron deficiency, B12 deficiency, myeloproliferative disorders)

A 42-year-old woman comes to the clinic with 3 months of fatigue and shortness of breath on climbing stairs. She has had 8-day menstrual periods with clots for the past year, and ultrasound previously showed a fibroid uterus. She has no abdominal pain, change in bowel habits, melena, or weight loss, takes no medications, is not pregnant, and eats a mixed diet. Examination shows conjunctival pallor and a normal abdominal examination. Laboratory results: hemoglobin 101 g/L (115-155), MCV 74 fL (80-100), ferritin 8 microg/L (15-200), total iron-binding capacity 85 micromol/L (45-80), transferrin saturation 0.10 (0.20-0.50).

Heart rate88/min
Respiratory rate16/min
Temperature36.8 °C
O2 saturation99%, room air
Blood pressure118/72 mm Hg

Question 1 of 12

Which one of the following is the most appropriate first-line therapy for her anemia?

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